ACE Inhibitors (angiotensin-converting enzyme inhibitors) pharmacology nursing review of the mechanism of action, side effects, nursing considerations etc.

ACE Inhibitors work to inhibit the RAAS (renin-angiotensin-aldosterone system). Therefore, when the angiotensin-converting enzyme is inhibited it prevents angiotensin I from converting to angiotensin II, which will help lower systematic vascular resistance and blood pressure.

Side effects of ACE inhibitors include: dry, persistent cough, hyperkalemia, hypotension, dizziness, and angioedema

Nursing considerations for ACE inhibitors include: assess blood pressure and pulse regularly, education about avoiding salt substitutes that contain potassium and avoiding a diet rich in potassium due to risk of hyperkalemia, monitoring for angioedema (swelling of the dermis and subcutaneous tissue...this is life threatening) etc.

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