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Ninja Nerds!
In this lecture Professor Zach Murphy will be teaching you about the structure and function of peroxisomes. After discussing the normal function of peroxisomes, we will go into USMLE step 1 disorders related to peroxisomal deficiencies. These will include Zellweger syndrome, Refsum's disease, and Adrenoleukodystrophy. We hope you enjoy this lecture and be sure to support us below!
Thanks to NN Community Friend @123awesome321 for the time stamps!
0:14 - Overview
0:32 - VLCFA, BCFA, & Peroxisome's ABCD1 Transporters
1:59 - F1: Beta-Oxidation of VLCFA Pathway (OHOT)
3:39 - F2: Alpha-Oxidation of BCFA Pathway
4:36 - F3: Ethanol Metabolism
5:49 - F4: Bile Acid Activation & Metabolism
6:37 - F5: Cholesterol Synthesis
8:11 - F6: Plasmalogen Synthesis
9:30 - F7: Catalase Activity for Reducing H2O2 Buildup
12:07 - Zellweger Syndrome
14:45 - Refssum's Disease
17:06 - Adrenoleukodystrophy (ALD)
19:12 - Comment, Like, SUBSCRIBE!
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