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https://www.ninjanerd.org/lecture/parkinsons-disease-drugs

Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:07 Parkinson’s Disease Medications Introduction
1:20 Basal Ganglia Anatomy
4:23 Direct vs. Indirect Pathway
18:23 Pathophysiology of Parkinson’s Disease
21:26 Drug Classes for Parkinson’s Disease
24:36 Mechanism of Action
38:51 L-Dopa + Carbidopa
1:00:22 Dopamine Agonists
1:06:08 COMT-Inhibitors
1:11:39 MAO-B-Inhibitors
1:20:12 Amantadine
1:27:10 Anticholinergics
1:31:18 PD Medications - Practice Problems
1:36:13 Comment, Like, SUBSCRIBE!

Supplemental Lectures:
Basal Ganglia - https://youtu.be/hxvep2Y8ShI

Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.

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