Paroxysmal Nocturnal Hemoglobinuria (PNH) | Causes & Pathogenesis, Symptoms, Diagnosis & Treatment

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Paroxysmal Nocturnal Hemoglobinuria (PNH) is an acquired hematologic (blood) condition involving irregular (paroxysmal) episodes of pink/red urine coloration that often occurs at night. The pathogenesis of this condition involves a mutation in a blood-making stem cell within the bone marrow. PNH is a very rare condition, often affecting individuals of certain age groups. In this lesson, we discuss the pathogenesis of PNH, along with the epidemiology, signs & symptoms, how PNH is diagnosed and how it is treated.

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JJ

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for EDUCATIONAL PURPOSES ONLY, and information presented here is NOT TO BE USED as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*