Lesson on Glucose-6-Phosphate Dehydrogenase Deficiency: Introduction, Pathophysiology, Signs and Symptoms, Diagnosis and Treatment. Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency is the most common inherited red blood cell disorder leading to hemolytic anemia. Decreased levels and activity of the Glucose-6-Phosphate Dehydrogenase enzyme leads to impaired functioning of the pentose phosphate pathway, reduced NADPH generation and reduced ability of the red blood cell to handle oxidative stress in the form of reactive oxygen species (ROS).

The majority of individuals with this condition are asymptomatic but have periods of acute hemolysis due to triggering factors. Triggers can include infections, medications like dapsone and primaquine, chemicals like naphthalene and henna, and foods like fava beans.

Hey everyone! This is a lesson on the blood disorder known as G6PD Deficiency. In this lesson, you will learn about the epidemiology of G6PD Deficiency, the role of the pentose phosphate pathway in the disease, signs and symptoms of this disease, tests to help diagnose the disease and treatments.

I hope you all find this video helpful. If you do, please like and subscribe for more videos like this one :)

JJ

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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JJ