Lesson on Methionine Metabolism and the Activated Methyl Cycle. Methionine is a sulfur-containing essential amino acid, which can be processed within the activated methyl cycle to produce s-adenosyl methionine (SAM) and tetrahydrofolate (THF). Methionine can also be metabolized to succinyl-CoA, which can then be utilized in the tricarboxylic acid (TCA) cycle to generate ATP. Two enzymes in these pathways, one in the activated methyl cycle and the other needed to produce succinyl-CoA, require vitamin B12 for there utilization.
Hey everyone. In this lesson you will be introduced to Methionine Metabolism and the related Activated Methyl Cycle. We will also discuss the purpose of the activated methyl cycle, the enzymes involved in each pathway, which vitamins are required for enzyme activity, and how methionine is converted into succinyl CoA for energy production.
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JJ
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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
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JJ