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In this video I introduce the biology of memory and the role of the hippocampus on long-term memory formation. I discuss several cases of severe memory loss including patients H.M. and E.P., who suffered anterograde amnesia and cannot form new memories, and Clive Wearing, who also suffers from retrograde amnesia and is unable to recall his past. These case studies reveal the role of the hippocampus in explicit memory formation and also demonstrate that procedural memory does not rely on the the hippocampus.

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E.P. Case Study (Scientific American Frontiers)
https://www.youtube.com/watch?v=CL-0gfpf_6g

Clive Wearing Documentary
https://www.youtube.com/watch?v=k_P7Y0-wgos&t=3s