Insulin Signaling Cascade and Downstream Effects Biochemistry Lesson

Insulin Signaling Cascade course, in this course delves into the intricate molecular pathways triggered by insulin binding to its receptor, regulating glucose metabolism and other cellular processes. Students will explore the key components of the insulin signaling cascade, including receptor activation, tyrosine phosphorylation, and downstream signaling events involving PI3K/Akt and MAPK pathways. Through lectures and laboratory demonstrations, learners will gain insights into the physiological effects of insulin on glucose uptake, glycogen synthesis, protein synthesis, and lipid metabolism. Additionally, we'll discuss the dysregulation of insulin signaling in metabolic disorders such as type 2 diabetes mellitus and potential therapeutic interventions targeting this pathway.