?What laboratory tests are commonly used in the diagnosis of Tumour Lysis Syndrome (TLS)

Common laboratory tests include measurement of serum electrolytes (such as potassium, phosphate, and calcium), renal function tests (including serum creatinine and blood urea nitrogen), uric acid levels, and assessment of tumor markers.

?How is Tumour Lysis Syndrome diagnosed clinically

Clinically, Tumour Lysis Syndrome may be diagnosed based on the presence of characteristic signs and symptoms, including hyperkalemia, hyperphosphatemia, hypocalcemia, hyperuricemia, and renal dysfunction, often accompanied by manifestations such as muscle cramps, nausea, vomiting, lethargy, and oliguria. Additionally, imaging studies like ultrasound or CT scans may reveal evidence of tumor burden and organ involvement.

Tumour Lysis Syndrome diagnosis and treatment Tutorial

What will you learn in this course?

Identify key clinical signs and symptoms of Tumour Lysis Syndrome in cancer patients and emergency settings
Interpret laboratory test results including electrolytes, renal function, and tumor burden for TLS diagnosis
Apply diagnostic criteria and risk assessment tools to accurately diagnose Tumour Lysis Syndrome
Evaluate the pathophysiology and risk factors contributing to TLS development in oncology patients

Implement effective laboratory and clinical assessment protocols for early TLS detection and management
Develop treatment strategies to prevent and manage electrolyte imbalances and renal failure in TLS
Utilize current guidelines and best practices for diagnosing and treating Tumour Lysis Syndrome
Recognize the importance of multidisciplinary approaches in the prompt diagnosis and management of TLS

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Lessons | 15